Bupropion is used to treat depression and seasonal affective disorder, and to help people quit smoking. Learn about side effects, warnings, dosage, and more. Indications The efficacy of bupropion as an antidepressant is comparable to the with bupropion at mg a day and benefit at doses of mg twice daily. Wellbutrin (Bupropion) is an antidepressant medication used for The FDA reapproved Wellbutrin in with a lowered daily dose and a. Effexor bipolar 2 attention should be paid to GI problems because of the possible development of paralytic ileus. Pain is also listed as a possible adverse reaction in 2 percent-3 percent of patients. Trihexyphenidyl: Moderate Additive anticholinergic effects may be seen when trihexyphenidyl is used concomitantly with bupropion. Wellbutrin XL extended-release bupropion hydrochloride tablets: Do not chew, cut, or crush tablets since coses may lead to an increased risk of adverse effects including seizures. Wellbutrin XL is indicated for depression. Important warnings. Topiramate: Moderate Bupropion should not be used by patients with a preexisting seizure disorder because it may lower the seizure please click for source. What about Sandoz? Lacosamide: Moderate Bupropion should not be used by patients with a preexisting seizure disorder because it may lower the seizure threshold. Clinicians should keep this in mind when using antimuscarinics and other medications with anticholinergic activity in combination with bupropion. Also, let the doctor know if there is a risk of seizures. The patient should be monitored for hypertensive reactions for two weeks or until 24 hours after the last dose of methylene blue, whichever comes first. It is approved for the treatment of major depressive disorder MDDseasonal affective disorder SADand to help people quit smoking smoking cessation. Patients should be warned to use caution when driving or operating machinery or performing other tasks that require mental alertness until they know how bupropion will affect them. Or you may not be able to quit smoking. Dosing may be weight based or may use otc allopurinol non-weight based titration similar to adults. In general the risk of seizures due to bupropion is low. A part of the extended-release tablet may pass into your stool.