Find a comprehensive guide to possible side effects including common and rare side effects when taking Wellbutrin (Bupropion Hcl) for healthcare professionals. Antidepressants, blood pressure drugs, and allergy medicines are some of the many popular medications that can affect your dreams, and not. Find information about common, infrequent and rare side effects of Wellbutrin XL Oral. I have done it in the past. OK everyone, It see more me again, another week has passed. However, none of these drugs have proven anti-depressant effects, and regular use poses the real risk of dependence and other medical njghtmares. I take one in the morning and the other at night. How long do I wait before knowing if this medication will work for me or not? There is some tendency for depressed people to experience more-distressing dreams than people who are not depressed; these usually reflect themes that are consistent with the worries and difficulties that accompany the depressive state.