Along with its needed effects, allopurinol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need . Uremia, hematuria, male infertility, impotence, erectile dysfunction. By lowering the production of uric acid, flare-ups of gout can be prevented. As this could potentially cause kidney problems, allopurinol is also sometimes used to prevent this. Erectile dysfunction or infertility in men. But a new study suggests that gout may also cause ED in most men suffering from it. such as allopurinol, used to treat gout, may be causing ED. Read More: 9 Amazing Facts About Protein Coffee and How It Can Change. The main use of allopurinol is in preventing attacks of gout, which occur as a result of a build-up of uric acid crystals in the joints. By lowering the production of uric acid, flare-ups of gout ccause be prevented. Pascual E. Conclusion The findings of this review indicated a positive association of gout and ED, but this work is hampered by the heterogeneity among included studies, allopurijol some extent. It was also clear from the studies that there is indeed a growing evidence of a connection between the condition of ED and gout. Hypersensitivity reactions.