In clinical studies with Effexor XR, tapering was achieved by reducing the daily dose by 75 mg at one-week intervals. Individualization of tapering may be. If you and your doctor decide to take you off venlafaxine, your doctor will probably recommend reducing your dose gradually to help prevent extra side effects. When stopping treatment with venlafaxine, the dose should be gradually reduced over a period of at least one to two weeks in order to reduce the risk of. Need help? Although rare, stopping Effexor on your own can result in severe and frightening reactions. Reducing effexor dose to your doctor if they last longer than a week this web page are severe. You may also be able to find groups on Facebook, in which members can offer each other tips and support. Will it affect my fertility? Teen Addiction. This might be gradually increased to a maximum dose of mg. Venlafaxine can be taken by adults for depression, anxiety and panic attacks. While effexxor will typically go away in a few weeks, there are ways to make Effexor withdrawal more tolerable during that time.